Search results for "blood smear"

showing 4 items of 4 documents

Vacuolated PAS-Positive Lymphocytes on Blood Smear: An Easy Screening Tool and a Possible Biomarker for Monitoring Therapeutic Responses in Late Onse…

2018

Background: Primary aim was to investigate the diagnostic value of PAS-positive vacuolated lymphocytes on blood smear in Late Onset Pompe Disease (LOPD) patients and, secondly, to evaluate its potential utility in monitoring treatment effects.Methods: We examined blood smear of 26 LOPD patients. We evaluated 10 treated and 16 untreated LOPD patients. Among the latter group, 7 patients later initiated ERT and were tested again 6 months after start. Blood smear was also sampled from 82 controls and 19 patients with other muscle glycogenoses (MGSDs). PAS staining was used to evaluate: (1) presence of lymphocytes with glycogen-filled vacuoles, (2) quantification of vacuolated lymphocytes.Result…

0301 basic medicinemedicine.medical_specialtytherapeutic monitoringBlood smear; LOPD screening test; PAS-positive lymphocytes; Pompe disease; Therapeutic monitoring; Neurology; Neurology (clinical)Late onsetPeriodic acid–Schiff stainDiseasePAS-positive lymphocytesGastroenterologylcsh:RC346-429Vacuolated Lymphocytes03 medical and health sciences0302 clinical medicineInternal medicineBlood smear; LOPD screening test; PAS-positive lymphocytes; Pompe disease; Therapeutic monitoringmedicineScreening toolLOPD screening testlcsh:Neurology. Diseases of the nervous systemOriginal Researchbusiness.industryPompe diseasePredictive value030104 developmental biologyBlood smearNeurologyblood smearBiomarker (medicine)Neurology (clinical)business030217 neurology & neurosurgeryFrontiers in neurology
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Morphological characterization of the blood cells in the endangered Sicilian endemic pond turtle,Emys trinacris(Testudines: Emydidae)

2014

AbstractIn this study, measurements of morphological parameters, sizes and frequencies of peripheral blood cells (erythrocytes, leukocytes, thrombocytes) on blood smear preparation devices stained with May-Grunwald stain were evaluated for both sexes in 20 Emys trinacris (Testudines: Emydidae) specimens. Erythrocytes were higher in male than in female specimens. The leukocyte of E. trinacris contains eosinophil, basophil, monocyte, heterophil and lymphocyte. The eosinophil was higher in males than in females whereas lymphocytes were higher in females than in males. The erythrocyte morphological parameters (EL [erythrocyte length], EW [erythrocyte width], L/W [length/width], ES [erythrocyte …

EmysbiologyEmys orbicularisLymphocyteEndangered speciesTurtle (syntax)Settore BIO/05 - ZoologiaZoologyEmydidaeAnatomyEosinophilbiology.organism_classificationmedicine.anatomical_structureblood smearEmys trinacrisEmys trinacris; blood smear; blood cell morphology; Trachemys scripta elegansmedicineblood cell morphologyAnimal Science and ZoologyEmys trinacriTrachemys scripta elegans
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Morphological and biometrical features of Trypanosoma evansi isolates from an outbreak in mainland Spain.

2011

According to several authors, Trypanosoma evansi is a monomorphic trypanosome found exclusively in slender intermediate forms, although additional studies have revealed that many strains present stumpy forms on rare occasions. In a recent T. evansi outbreak in mainland Spain, several atypical forms were observed in blood smear examinations. Molecular procedures were then necessary to confirm the causal agent. Morphological and biometric measures were taken to characterize the different forms of T. evansi. In contrast to published information, the results of this study would indicate that biometrically distinct T. evansi could also be found in the same farm and even in the same animal specie…

Veterinary medicineTrypanosomaCamelusGeneral VeterinarybiologyOutbreakGeneral MedicineTrypanosoma evansibiology.organism_classificationDisease OutbreaksBlood smearSpainTrypanosomiasisAnimalsParasitologyMainlandHorse DiseasesHorsesAnimal speciesVeterinary parasitology
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Trypanosoma evansi infection in mainland Spain.

2009

An outbreak of Trypanosoma evansi infection that occurred in mainland Spain is described. The outbreak occurred on an equine and camel farm to which dromedary camels from an infected area of the Canary Islands had recently been introduced. One of these camels developed clinical signs and T. evansi was discovered in a blood smear examination. The herd was evaluated in order to determine the extent of the disease. The results showed that 76% of the camels, 35% of the donkeys and 2% of the horses were affected. The animals were isolated and treated using Cymelarsan((R)) (0.5mg/kg). After treatment, three blood analysis using parasitological methods revealed negative results. This is the first …

endocrine systemVeterinary medicineTrypanosomaCamelusAntibodies ProtozoanBiologyCymelarsanPolymerase Chain ReactionArsenicalsDisease OutbreaksSeroepidemiologic StudiesTrypanosomiasisSeroprevalenceAnimalsGeneral VeterinaryOutbreakGeneral MedicineTrypanosoma evansiDNA Protozoanbiology.organism_classificationTrypanocidal AgentsBlood smearParasitologySpainHerdParasitologyMainlandVeterinary parasitology
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